Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CACNG2 | contributors: mct - updated : 08-02-2012 |
HGNC name | calcium channel, voltage-dependent, gamma subunit 2 |
HGNC id | 1406 |
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Corresponding disease |
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Location | 22q12.3 Physical location : 36.960.103 - 37.098.903 | ||
Synonym name | |||
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Synonym symbol(s) | MGC138502, MGC138504, TARP-G2, FLJ41437, CU012974, MRD10 |
DNA |
TYPE | functioning gene |
STRUCTURE | 138.80 kb 4 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D22S283 - CACNG2 ,D22S1177 - D22S423 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP , PhosphoP |
mono polymer | heteromer , pentamer |
HOMOLOGY |
interspecies | homolog to rattus Cacng2 (98.5 pc) |
homolog to murine Cacng2 (98.8 pc) |
Homologene |
FAMILY | |
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CATEGORY | structural protein , transport channel |
SUBCELLULAR LOCALIZATION | plasma membrane,junction,tight |
intracellular | |
intracellular,cytoplasm,cytosolic,vesicle | |
text | multi-pass membrane protein; concentrated in the postsynaptic area |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | development |
text | |
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PATHWAY |
metabolism |
signaling | neurotransmission |
transmission of nerve impulse |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
Other | phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4 |
ASSOCIATED DISORDERS |
corresponding disease(s) | MRD10 |
Susceptibility | to chronic pain following nerve injury |
Variant & Polymorphism other | |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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