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FLASH GENE
Symbol CACNA2D3 contributors: mct - updated : 04-01-2008
HGNC name calcium channel, voltage-dependent, alpha 2/delta 3 subunit
HGNC id 15460
Location 3p21.1      Physical location : 54.156.692 - 55.108.582
Synonym name
  • voltage-dependent calcium channel subunit alpha-2-3
  • dihydropyridine-sensitive L-type calcium channel subunits alpha-
  • 2/delta 3
    Synonym symbol(s) HSA272268
    DNA
    TYPE functioning gene
    STRUCTURE 951.00 kb     38 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    regionally located near the locus D3S1289
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    38 - 3689 123 1091 - Qin (2002)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx   highly
    Endocrineneuroendocrinepituitary  highly
    Nervousbrain   highly
    cell lineage
    cell lines different types of tumor
    fluid/secretion
    at STAGE
    physiological period fetal
    Text all tissues
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Cacna2d3
    Homologene
    FAMILY
  • alpha-2/delta subunit family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • having voltage-gated ion channel activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   LOH    
    in renal cell carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS