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FLASH GENE
Symbol CA6 contributors: npt/ - updated : 04-07-2006
HGNC name carbonic anhydrase VI
HGNC id 1380
Location 1p36.2      Physical location : 9.005.921 - 9.035.146
Synonym name
  • gustin
  • salivary carbonic anhydrase
  • carbonic anhydrase VI nirs variant 1
  • carbonic anhydrase VI nirs variant 3
  • Synonym symbol(s) CA-VI, MGC21256
    EC.number 4.2.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 29.23 kb     8 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1339 33.6 308 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivesalivary glandsubmaxillary   
     salivary glandparotid   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularexocrine 
    cell lineage
    cell lines
    fluid/secretion saliva
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a signal peptide at the N terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • eukaryotic-type carbonic anhydrase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text secretory granules
    basic FUNCTION
  • carbonic anhydrase
  • reversibly hydrating Co2 in cellular ion transport and pH homeostasis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS