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FLASH GENE

Symbol

CA6

contributors: npt/ - updated : 04-07-2006

HGNC name	carbonic anhydrase VI
HGNC id	1380

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	1p36.2      Physical location : 9.005.921 - 9.035.146
Synonym name	gustin
	salivary carbonic anhydrase
	carbonic anhydrase VI nirs variant 1
	carbonic anhydrase VI nirs variant 3
Synonym symbol(s)	CA-VI, MGC21256
EC.number	4.2.1.1

DNA

TYPE	functioning gene
STRUCTURE	29.23 kb     8 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed CA6 8 - 1339 33.6 308 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive salivary gland submaxillary         salivary gland parotid

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular exocrine

cell lineage
cell lines
fluid/secretion	saliva

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a signal peptide at the N terminus

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY

eukaryotic-type carbonic anhydrase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,vesicle
text	secretory granules

basic FUNCTION	carbonic anhydrase
	reversibly hydrating Co2 in cellular ion transport and pH homeostasis

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS