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FLASH GENE
Symbol C9orf116 contributors: mct - updated : 28/10/2008
HGNC name chromosome 9 open reading frame 116
HGNC id 28435
Location 9q34.3      Physical location : 138.387.025 - 138.391.761
Synonym name
  • pierce 1
  • hypothetical protein LOC138162
    • Synonym symbol(s) FLJ13945, MGC29761, RP11-426A6.4, PIERCE1
    DNA
    TYPE functioning gene
    STRUCTURE 4.74 kb     3 Exon(s)
    regulatory sequence Promoter
    text structure
  • strongly activated by TP53 via 2 cis-elements
    • MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 731 15.1 136 - -
    - - 685 10.2 92 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx    
    Reproductivemale systemtestis   
    Urinarykidney   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • an important TP53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TP53 target gene contributing to the ultraviolet-induced DNA damage response
    • cell & other
    REGULATION
    induced by genotoxic stresses that activate TP53
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS