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FLASH GENE

Symbol

C6orf108

contributors: - updated : 07-07-2005

HGNC name	chromosome 6 open reading frame 108
HGNC id	21218

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6p21.1      Physical location : 43.193.368 - 43.197.211
Synonym symbol(s)	RCL

DNA

TYPE	functioning gene
STRUCTURE	3.00 kb     4 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - splicing 662 19 174 - - variant 2 - splicing 813 16 148 - - inclusion of an additional segment in the 3' coding region compared to variant 1 causing a frameshift

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       predominantly   vessel       highly Digestive intestine large intestine colon   highly Respiratory lung       highly Urinary kidney       moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	ortholog to rattus Rcl
	ortholog to murine Rcl

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

may play a role during cellular proliferation and c-Myc-mediated transformation

CELLULAR PROCESS	cell life, proliferation/growth

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

Other

stimulated by c-Myc protein

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS