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FLASH GENE

Symbol

C4orf26

contributors: mct - updated : 15-10-2012

HGNC name	chromosome 4 open reading frame 26
HGNC id	26300

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Corresponding disease	AIH6 amelogenesis imperfecta, hypomaturation type 6
Location	4q21.1      Physical location : 76.481.257 - 76.489.927
Synonym name	hypothetical protein LOC152816
Synonym symbol(s)	FLJ23657

DNA

TYPE	functioning gene
STRUCTURE	9.85 kb     2 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_178497 2 - 1882 NP_848592 15 130 - 2012 22901946 NM_001206981 3 - 1926 NP_001193910 - 176 - 2012 22901946 NM_001257072 3 - 1746 NP_001244001 - 85 - 2012 22901946

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Urinary bladder

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text

placenta

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a predicted signal peptide (AAs 1–23) but no other recognizable domains or motifs
	phosphorylated C terminus has the capacity to promote nucleation of hydroxyapatite, suggesting a possible function in enamel mineralization during amelogenesis

HOMOLOGY

Homologene

FAMILY

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION

putative extracellular matrix acidic phosphoprotein expressed in the enamel organ

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

AIH6

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS