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FLASH GENE
Symbol C21orf59 contributors: mct - updated : 23-11-2013
HGNC name chromosome 21 open reading frame 59
HGNC id 1301
Corresponding disease
ICS27 immotile cilia syndrome 27
Location 21q22.11      Physical location : 33.973.983 - 33.984.918
Synonym name
  • chromosome 21 open reading frame 48
  • prostate cancer upregulated protein 1
    • Synonym symbol(s) C21orf48, FLJ20467, FLJ37137, FLJ40247, CILD26, FBB18
    DNA
    TYPE functioning gene
    STRUCTURE 11.20 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1427 - 290 - -
    - - 1064 33.2 290 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Respiratoryrespiratory tracttrachea    Rattus norvegicus
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a coiled-coil (CC)
  • a domain of unknown function (DUF2870) at the C-terminal end
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • may have an oxidoreductase activity
  • play essential roles in cilia function
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism other
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ICS27
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS