basic FUNCTION
| involved in locomotory behavior |
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C1QL1 undergoes RNA editing causing non-synonymous amino acid substitutions |
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may play diverse roles by forming homomeric and heteromeric complexes in the central nervous system |
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C1QL1, C1QL2, C1QL3, C1QL4 proteins are secreted signaling molecules that bind to ADGRB3 and act, at least in part, to regulate synapse formation and/or maintenance |
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C1QL1 and its receptor, the adhesion-GPCR brain angiogenesis inhibitor 3 (BAI3), controls the stereotyped pattern of connectivity established by excitatory afferents on cerebellar Purkinje cells |
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CQL1/Ctrp14 and C1QL4/Ctrp11 stimulate the new blood vessel growth by activation of ERK1/2 signal pathway |
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CBLN1 and C1QL1 proteins regulate the formation and maintenance of parallel fiber-Purkinje cell and climbing fiber-Purkinje cell synapses, respectively, in the cerebellum |
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play an important role in synaptic maturation, regulation, and maintenance in the central nervous system |
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is essential for development of hair cell innervation and outer hair cells survival |