Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol C11orf95 contributors: mct - updated : 05-11-2010
HGNC name chromosome 11 open reading frame 95
HGNC id
Location 11q13.1      Physical location : 63.527.364 - 63.536.113
Synonym name hypothetical protein LOC65998
Synonym symbol(s) MGC3032
DNA
TYPE functioning gene
STRUCTURE 8.75 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 5595 - 678 - 2010 20607705
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four polyglutamic rich and one proline rich region
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   translocation    
    t(11;16)(q13;p13), in C11orf95-MKL2 fusion oncogene in chondroid lipoma
    tumoral fusion      
    C11orf95-RELA fusions drive oncogenic NFKB signalling in ependymoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerbrain 
    C11orf95-RELA fusion protein is a potential therapeutic target in supratentorial ependymoma
    ANIMAL & CELL MODELS