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FLASH GENE
Symbol C11orf80 contributors: mct - updated : 27-11-2018
HGNC name chromosome 11 open reading frame 80
HGNC id 26197
Location 11q13.2      Physical location : 66.512.206 - 66.610.987
Synonym name hypothetical protein LOC79703
Synonym symbol(s) FLJ22531, TOP6BL, TOPOVIBL
DNA
TYPE functioning gene
STRUCTURE 98.78 kb     17 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
17 - 2323 - 677 - 2016 26917764
15 - 2031 - 511 - 2016 26917764
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland    
 parathyroid    
Nervousnerve    
Reproductivemale systemprostate   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY DNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,chromatin/chromosome
basic FUNCTION
  • MEI1, C11orf80, REC114 play a key role in the formation of double-strand breaks, which is essential for homologous chromosome synapsis and recombination during meiosis I
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS