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FLASH GENE
Symbol BZW2 contributors: mct/npt - updated : 03/10/2008
HGNC name basic leucine zipper and W2 domains 2
HGNC id 18808
Location 7p21.1      Physical location : 16.685.758 - 16.746.148
Synonym name basic leucine zipper and W2 domain-containing protein 2
Synonym symbol(s) HSPC028, MST017, MSTP017
DNA
TYPE functioning gene
SPECIAL FEATURE arranged in tandem
text see TSG7C, in the deleted region of WILMS tumor
STRUCTURE 60.39 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
CAV2 7q31.1-q31.2 caveolin 2 PFTK1 7q21-q13 PFTAIRE protein kinase 1 CAV1 7q31.2-q31.3 caveolin 1, caveolae protein, 22kDa LOC392637 7 similar to RIKEN cDNA 4930579E17 MET 7q31.2-q31.3 met proto-oncogene (hepatocyte growth factor receptor) SOSTDC1 7p21.2 sclerostin domain containing 1 LOC392638 7 similar to RIKEN cDNA 4933421E18 CAPZA2 7q31.2-q31.3 capping protein (actin filament) muscle Z-line, alpha 2 LOC346380 7p21.2 similar to ataxin 2 related protein isoform D; ataxin-2 domain protein DKFZP564O043 7p21 hypothetical protein DKFZp564O043 ST7 7q31.1-q31.3 suppression of tumorigenicity 7 LOC389467 7 similar to RIKEN cDNA 4930579E17 BZW2 7p21.3 basic leucine zipper and W2 domains 2 FZD1 7q21 frizzled homolog 1 (Drosophila) TM4SF13 7p21.1 transmembrane 4 superfamily member 13 AGR2 7p21.3 anterior gradient 2 homolog (Xenepus laevis) LOC392746 7 LOC392746 SOSTDC1 7p21.2 sclerostin domain containing 1 BCMP11 7p21.2 breast cancer membrane protein 11 LOC389468 7 similar to RIKEN cDNA 4933421E18 WNT2 7q31 wingless-type MMTV integration site family member 2 LOC317727 7p21 ataxin 2 related protein pseudogene DKFZP564O043 7p21 hypothetical protein DKFZp564O043 GASZ 7q31.31 GASZ BZW2 7p21.3 basic leucine zipper and W2 domains 2 TM4SF13 7p21.1 transmembrane 4 superfamily member 13 CFTR 7q31.3 cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) AGR2 7p21.3 anterior gradient 2 homolog (Xenepus laevis) BCMP11 7p21.2 breast cancer membrane protein 11 RAD17P1 7p21 RAD17 homolog (S. pombe) pseudogene 1 AHR 7p21-p15 aryl hydrocarbon receptor MTERF 7q21-q22 aryl hydrocarbon receptor CORTBP2 7q31.3 cortactin binding protein 2 AKAP9 7q21-q22 a kinase (PRKA) anchor protein (yotiao) 9 CYP51A1 7q21.2-q21.3 cytochrome P450, family 51, subfamily A, polypeptide 1 LOC392747 7 similar to hypothetical protein 4932412H11 CCM1 7q21-q22 cerebral cavernous malformations 1 AHR 7p21-p15 aryl hydrocarbon receptor SNX13 7p21.3 sorting nexin 13 LSM8 7q31.1-q31.3 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) LOC392951 7 similar to RIKEN cDNA 4930500J03 ANKRD7 7q31 ankyrin repeat domain 7 LOC392952 7 similar to RIKEN cDNA 2810014D17 ODAG 7q21-q22 ocular development-associated gene PEX1 7q21-q22 peroxisome biogenesis factor 1
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 1869 48 419 - Olsen (2006)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver    
Endocrinepancreas   highly
Nervousbrain    
Reproductivefemale systemplacenta  highly
 male systemprostate  highly
Respiratoryrespiratory tractlarynx  highly
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an eIF4-gamma/eIF5/eIF2-epsilon domain
  • HOMOLOGY
    interspecies homolog to murine Bzw2
    homolog to Drosophila eif-5c
    Homologene
    FAMILY
  • BZW family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, transcription, initiation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS