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FLASH GENE
Symbol BTN3A2 contributors: - updated : 17-11-2006
HGNC name butyrophilin, subfamily 3, member A2
HGNC id 1139
Location 6p22.1      Physical location : 26.365.397 - 26.378.546
Synonym symbol(s) BTN3, BTN3A, BT3.2, BTF4
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text located in the juxta-telomeric region of the MHC1 locus, on chromosome 6, in the seven member BTN cluster
STRUCTURE 13.00 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
HIST1H3D 6p21.3 histone 1, H3d HIST1H2AD 6p21.3 histone 1, H2ad HIST1H2BF 6p21.3 histone 1, H2bf HIST1H4E 6p21.3 histone 1, H4e HIST1H2BG 6p21.3 histone 1, H2bg HIST1H2AE 6p21.3 histone 1, H2ae HIST1H3E 6p21.3 histone 1, H3e HIST1H1D 6p21.3 histone 1, H1d HIST1H4F 6p21.3 histone 1, H4f HIST1H4G 6p21.3 histone 1, H4g HIST1H3F 6p21.3 histone 1, H3f HIST1H2BH 6p21.3 histone 1, H2bh HIST1H3G 6p21.3 histone 1, H3g HIST1H2APS4 6p21.3 histone 1, H2a, pseudogene 4 HIST1H2BI 6p21.3 histone 1, H2bi HIST1H4H 6p21.3 histone 1, H4h BTN3A2 6p22.1 butyrophilin, subfamily 3, member A2 BTN2A2 6p22.1 butyrophilin, subfamily 2, member A2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Ig domains with similarity to Ig variable and Ig constant domains
  • a transmembrane segment
  • a short cytoplasmic tail with four short exons (7 and 9AA)
  • carboxyterminal B30.2 domain
  • HOMOLOGY
    Homologene
    FAMILY
  • B box family of proteins
  • butyrophilin subfamily 3
  • CATEGORY immunity/defense , regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral to membrane
    basic FUNCTION involved in cell proliferation and development
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS