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FLASH GENE
Symbol BTN3A2 contributors: - updated : 17-11-2006
HGNC name butyrophilin, subfamily 3, member A2
HGNC id 1139
Location 6p22.1      Physical location : 26.365.397 - 26.378.546
Synonym symbol(s) BTN3, BTN3A, BT3.2, BTF4
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text located in the juxta-telomeric region of the MHC1 locus, on chromosome 6, in the seven member BTN cluster
STRUCTURE 13.00 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Ig domains with similarity to Ig variable and Ig constant domains
  • a transmembrane segment
  • a short cytoplasmic tail with four short exons (7 and 9AA)
  • carboxyterminal B30.2 domain
    • HOMOLOGY
    Homologene
    FAMILY
  • B box family of proteins
  • butyrophilin subfamily 3
    • CATEGORY immunity/defense , regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral to membrane
    basic FUNCTION involved in cell proliferation and development
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS