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FLASH GENE
Symbol BTBD3 contributors: mct - updated : 30-03-2018
HGNC name BTB (POZ) domain containing 3
HGNC id 15854
Location 20p12.2      Physical location : 11.871.476 - 11.907.242
Synonym name
  • related to C elegans cos F38H4
  • BTB domain containing 3
  • Synonym symbol(s) dJ742J24.1, KIAA0952, MGC130038, MGC130039
    DNA
    TYPE functioning gene
    STRUCTURE 35.87 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    C20orf103 20p12 chromosome 20 open reading frame 103 PAK7 20p12 p21(CDKN1A)-activated kinase 7 ANKRD5 20pter-q11.23 ankyrin repeat domain 5 SNAP25 20p12-p11.2 synaptosomal-associated protein, 25kDa RPL23AP6 20p12.2 ribosomal protein L23a pseudogene 6 LOC284773 20p12.2 similar to hypothetical protein FLJ10498 MKKS 20p12 McKusick-Kaufman syndrome LOC128710 20p12.2 similar to RIKEN cDNA 2210009G21 JAG1 20p12.1-p11.23 jagged 1 (Alagille syndrome) FAT1P1 20 FAT tumor suppressor homolog 1 (Drosophila) pseudogene 1 RPS11P1 20p12.1 ribosomal protein S11, pseudogene 1 PGAM3P 20p12.1 phosphoglycerate mutase 3, pseudogene BTBD3 20p12.1 BTB (POZ) domain containing 3 PA2G4P2 20p12.1 proliferation-associated 2G4 pseudogene 2 C20orf38 20p12.1 chromosome 20 open reading frame 38 C20orf82 20p12.1 chromosome 20 open reading frame 82 C20orf13 20p12.1 chromosome 20 open reading frame 13 GAPDP2 20p12 glyceraldehyde-3-phosphate dehydrogenase pseudogene 2 MRPS36P6 20p12.1 mitochondrial ribosomal protein S36 pseudogene C20orf6 20p12.1 chromosome 20 open reading frame 6 C20orf7 20p12.1 chromosome 20 open reading frame 7 C20orf50 20p12.1 chromosome 20 open reading frame 50 C20orf133 20p12.1 chromosome 20 open reading frame 133 RPS3P1 20p12 ribosomal protein S3 pseudogene 1 SCYE1P 20 small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) pseudogene FLRT3 20p11 fibronectin leucine rich transmembrane protein 3
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 4925 58.3 522 - 2002 12421765
    5 - 4688 - 565 - 2002 12421765
    4 - 4597 - 371 - 2002 12421765
    5 - 4507 51.4 461 - 2002 12421765
    5 - 4603 51.4 461 - 2002 12421765
    4 - 4512 - 371 - 2002 12421765
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one BTB/POZ domain
  • HOMOLOGY
    interspecies homolog to C.elegans cosmid F38H4
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • during the development of the sensory cortex, dendritic field orientation is controlled by the BTB/POZ domain-containing 3 (BTBD3)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • LHX2 confers neuronal competency for activity-dependent dendritic development in L4 neurons by inducing the expression of BTBD3
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in hepatocellular carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS