Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol BTBD3 contributors: mct - updated : 30-03-2018
HGNC name BTB (POZ) domain containing 3
HGNC id 15854
Location 20p12.2      Physical location : 11.871.476 - 11.907.242
Synonym name
  • related to C elegans cos F38H4
  • BTB domain containing 3
  • Synonym symbol(s) dJ742J24.1, KIAA0952, MGC130038, MGC130039
    DNA
    TYPE functioning gene
    STRUCTURE 35.87 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 4925 58.3 522 - 2002 12421765
    5 - 4688 - 565 - 2002 12421765
    4 - 4597 - 371 - 2002 12421765
    5 - 4507 51.4 461 - 2002 12421765
    5 - 4603 51.4 461 - 2002 12421765
    4 - 4512 - 371 - 2002 12421765
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one BTB/POZ domain
  • HOMOLOGY
    interspecies homolog to C.elegans cosmid F38H4
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • during the development of the sensory cortex, dendritic field orientation is controlled by the BTB/POZ domain-containing 3 (BTBD3)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • LHX2 confers neuronal competency for activity-dependent dendritic development in L4 neurons by inducing the expression of BTBD3
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in hepatocellular carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS