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FLASH GENE

Symbol

BRS3

contributors: npt/ - updated : 06-02-2007

HGNC name	bombesin-like receptor 3
HGNC id	1113

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	Xq26-q28      Physical location : 135.570.124 - 135.574.598
Synonym name	releasing peptide receptor, epidermal carcinoma
	G-protein coupled receptor
Synonym symbol(s)	BRS-3

DNA

TYPE	functioning gene
STRUCTURE	4.47 kb     3 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed BRS3 3 - 1413 44.3 399 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis

cell lineage	germ cells
cell lines	lung carcinomas cells
fluid/secretion

at STAGE

physiological period

pregnancy

Text	uterus pregnant

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to murine Brs3

Homologene

FAMILY	G protein coupled receptor 1 family
	bombesin receptor family

CATEGORY

motor/contractile , receptor membrane G

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

activating by association with G proteins a phosphadylinositol-calcium second messenger system, involved in sperm cell division, maturation, function

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

reproduction/sex

PATHWAY

metabolism

carbohydrate

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

G protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS