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FLASH GENE
Symbol BRS3 contributors: npt/ - updated : 06-02-2007
HGNC name bombesin-like receptor 3
HGNC id 1113
Location Xq26-q28      Physical location : 135.570.124 - 135.574.598
Synonym name
  • releasing peptide receptor, epidermal carcinoma
  • G-protein coupled receptor
  • Synonym symbol(s) BRS-3
    DNA
    TYPE functioning gene
    STRUCTURE 4.47 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC340581 Xq26.3 hypothetical protein LOC340581 LOC392545 X similar to high mobility group protein homolog HMG4 LOC389887 X similar to RIKEN cDNA 1110012O05 CXX1 Xq26 CAAX box 1 DKFZP564B147 Xq26.3 DKFZP564B147 protein LOC159049 Xq26.3 hypothetical LOC159049 FLJ20527 Xq26.3 hypothetical protein FLJ20527 LOC392546 X similar to hypothetical protein FLJ20527 LOC389888 X similar to hypothetical protein FLJ20527 LOC389889 X hypothetical gene supported by BC061642 ZNF75 Xq26 zinc finger protein 75 (D8C6) FLJ23614 Xq26.3 hypothetical protein FLJ23614 LOC392547 X similar to KIAA0445 protein LOC203522 Xq26.3 hypothetical protein LOC203522 LOC392548 X similar to C-ets-2 protein LOC139587 Xq26.3 similar to sarcoma antigen; putative tumor antigen MGC27005 Xq26.3 hypothetical protein MGC27005 SAGE Xq28 hypothetical protein MGC27005 LOC93380 Xq26.3 hypothetical protein LOC93380 SLC9A6 Xq26.3 solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 LOC392549 X similar to Glyceraldehyde 3-phosphate dehydrogenase, liver (GAPDH) LOC139542 Xq26.3 similar to E2F transcription factor 6 isoform a FHL1 Xq26 four and a half LIM domains 1 FLJ12649 Xq26.3 hypothetical protein FLJ12649 GPR112 Xq26.3 G protein-coupled receptor 112 BRS3 Xq26-q28 bombesin-like receptor 3 HTATSF1 Xq26-Xq27 HIV TAT specific factor 1 VGLL1 Xq26.3 vestigial like 1 (Drosophila) TNFSF5 Xq26 tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) ARHGEF6 Xq26 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 LOC392550 X similar to ribosomal protein L7 LOC392551 X similar to Ras-related protein Rab-28 (Rab-26) RBMX Xq26 RNA binding motif protein, X chromosome LOC389890 X hypothetical gene supported by AF419855; NM_005839 LOC389891 X similar to ENSANGP00000013187 GPR101 Xq25-27.1 G protein-coupled receptor 101 LOC286472 Xq26.3 similar to Ras-related C3 botulinum toxin substrate homolog DJ20J23.1 ZIC3 Xq26.2 Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) LOC389892 X similar to Mothers against decapentaplegic homolog interacting protein (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 1413 44.3 399 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis   
    cell lineage germ cells
    cell lines lung carcinomas cells
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text uterus pregnant
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Brs3
    Homologene
    FAMILY
  • G protein coupled receptor 1 family
  • bombesin receptor family
  • CATEGORY motor/contractile , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • activating by association with G proteins a phosphadylinositol-calcium second messenger system, involved in sperm cell division, maturation, function
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS reproduction/sex
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • G protein
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS