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FLASH GENE
Symbol BROX contributors: npt/mct - updated : 27/10/2008
HGNC name chromosome 1 open reading frame 58
HGNC id 26512
Location 1q41      Physical location : -
Genatlas name Bro1-domain-containing protein
Synonym name hypothetical protein LOC148362
Synonym symbol(s) C1orf58, FLJ32421, MGC142195, MGC142197, RP11-452F19.1, BROFTI
DNA
TYPE functioning gene
STRUCTURE 20.20 kb     13 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1686 46.3 411 - Ichioka (2007)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx    
Respiratoryrespiratory tracttrachea  highly
Urinarybladder    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a Bro1 domain-like sequence
  • a C-terminal thioester-linkage site of isoprenoid lipid (CAAX motif)
  • HOMOLOGY
    Homologene
    FAMILY
  • BROX family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS