protein
| is a LAMTOR1-interacting protein that regulates MTOR activity through its interaction with LAMTOR1 at the lysosome |
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upregulated in CD4+ T cells by either ADRB3 stimulation or cold exposure, suggesting contribution to Treg induction |
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is the linker between BORC and late endosomal/lysosomal adaptor and mitogen activated protein kinase and mechanistic target of rapamycin activator (LAMTOR) complexes |
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interaction of LAMTOR1 with Rag GTPases is required for their cellular co-localization and can be competitively inhibited by BORCS6 |