basic FUNCTION
| involved in cell proliferation or cell-cycle regulation |
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acting as a transcription regulator |
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heterotrimeric complex can work as a [2Fe-2S](2+) cluster transfer component in cytosolic Fe/S protein maturation pathways |
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BOLA2 plays critical roles in promoting iron overload, tumor growth and tumor hemorrhage (TH) |
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BOLA2 plays an important role in cancer biology and is an independent predictor of prognosis in hepatocellular carcinoma (HCC) |
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participates in iron homeostasis, and its expansion has a potential adaptive role in protecting against iron deficiency |
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involved in the maturation of cytosolic iron-sulfur proteins |