| basic FUNCTION
| putative protease, osteogenic protein |
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isolated from bone matrix, but it may have additional regulatory roles in the morphogenesis and/or function of the kidney, limb bud, tooth, heart, and intestine  |
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playing a role in calcium regulation and bone homeostasis |
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stimulating initial dendritic growth in sympathetic neurons through an intracellular fibroblast growth factor signaling pathway |
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important regulator of cell development and differentiation of various organs |
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increasing chick photoreceptor outer segment initiation |
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antagonist of TGFB2 in human trabecular meshwork cells |
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plays an important role during fetal kidney development, and a physiological role mostly in distal nephron |
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promotes differentiation of brown preadipocytes even in the absence of the normally required hormonal induction cocktail |
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playing an important role in promoting brown adipocyte differentiation and thermogenesis |
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having a specific effect on induction of the brown-fat-specific protein UCP1 |
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key protein involved in liver organogenesis and development, and playing a role as a kidney- and bone-produced endogenous regulator of hepatocyte health |
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may play an important role in the pathogenesis of myelofibrosis in primary myelofibrosis and are apparently induced by cytokines such as TGFbeta-1 |
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can promote and inhibit cell growth in breast cancer cell lines and, in a suitable environment, can also considerably induce breast cancer cell migration and invasion |
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BMP7 signaling through ACVR1 can reduce Wnt signaling via SOST/DKK1 and then inhibits osteogenesis |
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BMP7/JNK signaling regulates remodeling of the cloacal endoderm resulting in a topological separation of the urinary and digestive systems |
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inhibits epithelialization and differentiation of the kidney progenitor cells |
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regulation of BMP7 signaling is critical for renal development and renal disease progression |
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BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells |
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BMP2 and BMP7 both promoted odontogenic and osteogenic differentiation of tooth germ stem cells (hTGSCs) |
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SHH and BMP7, which are expressed in the anterior and posterior hypothalamic ventral midline respectively, together repel hypothalamic axons towards the medial ventral midline |
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BMP7 and EREG expression in late bell-stage human dental papilla contributes to the inductive potential of dental mesenchyme |
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protective BMP7 signaling may be facilitated by stress-inducible SCUBE1 after renal ischemia-reperfusion (I/R) |
