Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol BCL8 contributors: - updated : 28-02-2007
HGNC name B-cell CLL/lymphoma 8
HGNC id 1007
Location 15q11-q13      Physical location : 20.874.796 - 20.961.480
Synonym symbol(s) BCL8A
DNA
TYPE functioning gene
STRUCTURE 86.00 kb     3 Exon(s)    multiple Copie(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Endocrinepancreas   lowly
Reproductivemale systemtestis   
 male systemprostate   
Urinarykidney   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
interspecies homolog to C.elegans F10.f2.1
intraspecies homolog to LRBA
Homologene
FAMILY BCL8 family
CATEGORY enzyme , protooncogene
SUBCELLULAR LOCALIZATION
basic FUNCTION presumptive protein kinase A anchoring function
CELLULAR PROCESS cell life, antiapoptosis
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   translocation    
diffuse large-cell lymphomas (DLCL)with recurrent translocations affecting the chromosomal region 15q11-13 and various other partners
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS