Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol BCDIN3D contributors: mct - updated : 29-05-2018
HGNC name BCDIN3 domain containing
HGNC id 27050
Location 12q13.13      Physical location : 50.229.826 - 50.236.912
EC.number 2.1.1.-
DNA
TYPE functioning gene
STRUCTURE 5.32 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 1495 33.1 292 - 2012 23063121
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland   moderately
Lymphoid/Immunetonsils   predominantly
Reproductivefemale systemovary  highly
 female systemuteruscervix highly
Urinarybladder   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a BIN3 domain
  • HOMOLOGY
    interspecies homolog to rattus Bcdin3d (81.5 pc)
    homolog to murine Bcdin3d (79.7 pc)
    intraspecies homolog to BCDIN3
    Homologene
    FAMILY
  • methyltransferase superfamily, Bin3 family of putative methyltransferases
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    text
  • BCDIN3D is localized in the cytoplasm
  • basic FUNCTION
  • being a probable methyltransferase
  • is a RNA-methyltransferase that phospho-dimethylates 5&
  • 8242; monophosphate ends
  • enzyme defining a miRNA methylation pathway that antagonizes the DICER1-dependent processing of miRNAs and that has potential as a therapeutic target in cancer
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
  • S-adenosyl-L-methionine
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS