Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol BAAT contributors: - updated : 06-07-2006
HGNC name bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)
HGNC id 932
Location 9q22.3      Physical location : 104.122.699 - 104.147.287
Synonym name glycine N-choloyl transferase
Synonym symbol(s) BACAT, BAT
EC.number 2.3.1.65, 3.1.2.2
DNA
TYPE functioning gene
STRUCTURE 24.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Map cen - D9S180 - D9S1711 - D9S1272 - D9S272 - COL15A1 - ALDOB ALDOB - BAAT - D9S22 - D9S176 - qter
Authors Lench (96)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   specific
Endocrinepancreas    
Respiratorylung    
cells
SystemCellPubmedSpeciesStageRna symbol
Endocrineislet cell (alpha,beta...)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , monomer
HOMOLOGY
interspecies homolog to murine Baat
homolog to rattus Baat (69.6pc)
homolog to murine Baat (68.6pc)
Homologene
FAMILY
  • C/M/P thioester hydrolase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • catalyzing the transfer of the bile acid moiety from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates
  • acting as a serine esterase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein , organic acid
    signaling
  • bile acid metabolism
  • fatty acid metabolism
    • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional germinal mutation      
    in familial hypercholanemia
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS