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Symbol B3GNT6 contributors: npt - updated : 06-03-2004
HGNC name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
HGNC id 24141
Location 11q13.4      Physical location : 76.745.434 - 76.753.003
Synonym name
  • UDP-GlcNAc:GalNAc-peptide beta-1,3-N-acetylglucosaminyltransferase
  • core 3 synthase
  • beta-1,3-N-acetylglucosaminyltransferase protein
  • Synonym symbol(s) UGB3GNT6, B3GNT6, MGC119334, MGC119336, MGC119337, iGAT, iGNT
    EC.number 2.4.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 7.00 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 2510 42 384 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestine   
     intestinesmall intestine   
     stomach    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • beta3Gn-T family
  • glycosyltransferase 31 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type II membrane protein
    basic FUNCTION
  • transferring a GlcNAc to the GalNAc residue on MUC1 mucin, resulting in the synthesis of a core 3 structure
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS