Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ATP9B contributors: mct/npt - updated : 02-02-2013
HGNC name ATPase, Class II, type 9B
HGNC id 13541
Location 18q23      Physical location : 76.829.396 - 77.138.280
Synonym name
  • ATPase type IV, phospholipid transporting (P-type)(putative)
  • probable phospholipid-transporting ATPase IIB
  • Synonym symbol(s) ATPIIB, ATPASEP, ATPC2B, FLJ46612, HUSSY-20, MGC150650, MGC150651, MGC61572, NEO1L
    EC.number 3.6.3.1
    DNA
    TYPE functioning gene
    STRUCTURE 308.87 kb     30 Exon(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC284275 18q23 hypothetical LOC284275 KIAA0222 18q23 hypothetical LOC284275 ZNF236 18q22-q23 zinc finger protein 236 MBP 18q23 myelin basic protein LOC388483 18 LOC388483 GALR1 18q23 galanin receptor 1 LOC390864 18 similar to amino acid feature: Rod protein domain, aa 266 .. 468; amino acid feature: globular protein domain, aa 32 .. 265 LOC125595 18q23 hypothetical LOC125595 LOC390865 18 similar to hypothetical protein LOC390866 18 LOC390866 LOC390867 18 similar to Splicing factor 3A subunit 2 (Spliceosome associated protein 62) (SAP 62) (SF3a66) LOC390868 18 similar to hypothetical protein LOC388484 18 LOC388484 SALL3 18q23 sal-like 3 (Drosophila) ATP9B 18q23 ATPase, Class II, type 9B NFATC1 18q23 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 LOC388485 18 LOC388485 LOC390869 18 similar to immediate early protein homolog LOC147294 18q23 similar to immediate early protein homolog FLJ25715 18q23 hypothetical protein FLJ25715 CTDP1 18q23 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 LOC390870 18 LOC390870 KCNG2 18q22-q23 potassium voltage-gated channel, subfamily G, member 2 FLJ22378 DIM1 FLJ21172 18q23 hypothetical protein FLJ21172 KIAA0863 18q23 KIAA0863 protein PARD6G 18q23 par-6 partitioning defective 6 homolog gamma (C. elegans)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    30 - 4378 - 1147 - 2005 16177791
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunethymus   highly
    Nervousbrain    
     nerve   highly
    Reproductivemale systemprostate  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N-terminal cytoplasmic region of ATP9B contains a potential Golgi localization signal
  • HOMOLOGY
    interspecies homolog to murine Atp9b
    ortholog to putative orthologue of yeast Neo1p
    intraspecies homolog to ATP9A
    Homologene
    FAMILY
  • cation transport ATPase (P-type) family
  • type IV subfamily
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    intracellular,nuclear envelope
    text
  • integral membrane protein
  • localized exclusively to the TGN
  • basic FUNCTION
  • ATP9A and ATP9B are able to exit the ER in the absence of coexpressed TMEM30A or TMEM30B
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • requires neither TMEM30A nor TMEM30B for its localization to the trans-Golgi network (TGN), although most human P4-ATPases require CDC50 proteins (primarily CDC50A)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS