Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ATP6V1G3 contributors: mct/npt - updated : 30-04-2010
HGNC name ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
HGNC id 18265
Location 1q31.3      Physical location : 198.492.355 - 198.510.075
Synonym name
  • ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 3
  • V-ATPase 13 kDa subunit 3
  • vacuolar proton pump, subunit G3
  • Synonym symbol(s) VMA10, ATP6G3, MGC119810, MGC119813
    EC.number 3.6.3.14
    DNA
    TYPE functioning gene
    STRUCTURE 17.72 kb     4 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 645 - 118 - Forgac (1999)
    5 - 691 - 59 - Forgac (1999)
    an internal segment of sequence causing a frameshift
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemprostate   
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an ATP catalytic site
  • HOMOLOGY
    Homologene
    FAMILY
  • V-ATPase G subunit family
  • CATEGORY enzyme , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • multisubunit enzyme mediating acidification of eukaryotic intracellular organelles
  • in the epididymis and vas deferens, the vacuolar H(+)ATPase (V-ATPase), located in the apical pole of narrow and clear cells, is required to establish an acidic luminal pH and also participates in the acidification of intracellular organelles (Pietrement 2006)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text proton transport
    PATHWAY
    metabolism
    signaling
    a component
  • component of vacuolar ATPase (V-ATPase)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS