Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ATP6V1D contributors: np/ - updated : 20-09-2004
HGNC name ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
HGNC id 13527
Location 14q23.3      Physical location : 67.804.589 - 67.826.591
Synonym name
  • V-ATPase D subunit
  • vacuolar H-ATPase subunit D
  • ATPase, H+ transporting, lysosomal, 28 kD accessory protein
  • H(+)-transporting two-sector ATPase, subunit M
  • V-type proton ATPase subunit D
  • Synonym symbol(s) VATD, VMA8, ATP6M
    EC.number 3.6.3.14, 3.6.1.34
    DNA
    TYPE functioning gene
    STRUCTURE 22.00 kb     9 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    NSEP1P 14q23.2 nuclease sensitive element binding protein 1 pseudogene LOC122438 14q23.3 similar to RIKEN cDNA 1110013H04 LOC387993 14 hypothetical gene supported by BC033546 GPHN 14q23.1/14q23,3 gephyrin C14orf54 14 chromosome 14 open reading frame 54 LOC260329 14q23 splicing factor 3b, subunit 4, 49kD pseudogene MPP5 14q23.3 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) ATP6V1D 14q23-q24.2 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D EIF2S1 14q21.3 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa PLEK2 14q23.1-q23.2 pleckstrin 2 FLJ33387 14q24.1 hypothetical protein FLJ33387 PIGH 2p21-p16 phosphatidylinositol glycan, class H LOC390490 14 similar to Ac2-008 ARG2 14q24.1-q24.3 arginase, type II VTI1B 14q23,3 vesicle transport through interaction with t-SNAREs homolog 1B (yeast) COX7A3P 14 cytochrome c oxidase subunit VIIa polypeptide 3 pseudogene RDH11 14q23-q24.3 retinol dehydrogenase 11 (all-trans and 9-cis) RPL21P9 14q23.3 ribosomal protein L21 pseudogene 9 RDH12 14q23.3 retinol dehydrogenase 12 (all-trans and 9-cis) ZFYVE26 14q23.2-q24.2 zinc finger, FYVE domain containing 26 RAD51L1 14q24.1 RAD51-like 1 (S. cerevisiae) RPL7AP5 14 ribosomal protein L7a pseudogene 5
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 1823 - 247 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    mono polymer heteromer , octamer
    HOMOLOGY
    interspecies homolog to yeast S.cerevisiae Vma8p
    ortholog to murine Atp6m
    homolog to C.elegans f55h2.2
    intraspecies
    Homologene
    FAMILY
  • V-ATPase d subunit family
  • CATEGORY enzyme , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,lysosome
    text vacuole; attached to an integral membrane Vo proton pore complex
    basic FUNCTION
  • ATP synthesis
  • acidifying a variety of intracellular compartments using its proton-pumping action
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS active transport
    text hydrogen ion transport
    PATHWAY
    metabolism energetic , drug , other
    signaling
    ATP synthesis
    a component
  • vacuolar H+ ATPase (V-ATPase) subunit
  • subunit of the peripheral V1 complex of vacuolar ATPase
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • Vo proton pore complex
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS