Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ATP5A1 contributors: mct - updated : 02-05-2013
HGNC name ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle
HGNC id 823
Corresponding disease
ATP5A1D ATP5A1 deficiency
Location 18q21.1      Physical location : 43.664.109 - 43.684.199
Synonym name
  • ATP synthase, coupling factor
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2
  • mitochondrial ATP synthetase, oligomycin-resistant
  • ATP sythase (F1-ATPase) alpha subunit
  • Synonym symbol(s) ATP5A, ATP5AL2, ATPM, OMR, ORM, hATP1, MOM2
    EC.number 3.6.1.14
    DNA
    TYPE functioning gene
    STRUCTURE 14.18 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1842 - 503 - -
    13 - 1950 - 553 - -
    12 - 1895 - 553 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestivestomach   highly
    Lymphoid/Immunethymus   highly
    Visualeye   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumcardiac  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • nucleotide binding sites
  • isoforms Precursor
    HOMOLOGY
    Homologene
    FAMILY
  • ATPase alpha/beta chains family
  • CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,mitochondria,matrix
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • ATP synthesis, catalytic unit
  • oligomycin-resistant
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    oxydative phosphorylation
    a component
  • constituent of mitochondrial matrix F1 segment
  • component of complex V of oxidative phosphorylation (OXPHOS)
  • INTERACTION
    DNA
    RNA
    small molecule
  • ADP, ATP, Pi binding
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ATP5A1D
    related resource MITOP database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS