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FLASH GENE

Symbol

ATP1A4

contributors: mct - updated : 21-02-2018

HGNC name	ATPase, Na+/K+ transporting, alpha 4 polypeptide
HGNC id	14073

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	1q22      Physical location : 160.121.351 - 160.156.766
Synonym name	ATPase, Na+/K+ transporting, alpha polypeptide-like 2
	Na,K-ATPase subunit alpha-C
Synonym symbol(s)	ATP1AL2, RP11-536C5.5, ATP1A1
EC.number	3.6.3.9

DNA

TYPE	functioning gene
SPECIAL FEATURE	arranged in tandem
text	arranged in tandem with ATP1A2
STRUCTURE	35.00 kb     22 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed V1 - - 3873 - 1029 - Lingrel V2 - - 951 - 165 - Lingrel

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis       Urinary bladder

cell lineage
cell lines	cDNA transfected 3T3 cells
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

cation transport ATPase (p-type) family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION	involved in osmotic balance and cell volume stability
	catalyzing the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma
	involved in specialized functions of various tissues, helping to explain their tissue- and developmental-specific regulation membrane

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

active transport

text	Na+,K+ pump

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	nucleotide,
	ATP

protein

GPNMB promotes glioma growth via ATP1A1, ATP1A2, ATP1A3, ATP1A4

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS