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FLASH GENE
Symbol ATP12A contributors: - updated : 11-01-2006
HGNC name ATPase, H+/K+ transporting, nongastric, alpha polypeptide
HGNC id 13816
Location 13q12.1-q12.3      Physical location : 25.254.548 - 25.285.921
Synonym name ATPase, Na+/K+ transporting, alpha polypeptide-like 1
Synonym symbol(s) ATP1AL1
EC.number 3.6.3.10
DNA
TYPE anonymous DNA segment
STRUCTURE 31.00 kb     23 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked Y status confirmed
Map pter - D13Z1 - D13S11 - ATP12A - D13S283 - D13S179E - D13S504E /D13S505E - D13S824E - D13S182E - D13S221 - SLC7A1 - D13S6 - D13S33 - D13S1 - qter
Authors Bowcock (92),Still (97)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivemale systemtestis   
Respiratorylung    
Skin/Tegumentskin    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier/lining   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated PhosphoP
HOMOLOGY
interspecies ortholog to murine Atp12a
Homologene
FAMILY cation transport ATPase (p-type) family, type IIc subfamily
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
text integral membrane protein
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component non gastric form associating with gastric H+ K+ ATPase beta subunit
INTERACTION
DNA
RNA
small molecule metal binding, nucleotide,
  • ATP
  • magnesium Mg2+
  • protein
    cell & other
    REGULATION
    inhibited by ouabain
    PKC activation
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to murine Atp12a
    Homologene
    FAMILY ATPases family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral membrane protein
    basic FUNCTION non gastric form associating with gastric H+ K+ ATPase beta subunit,ouabaine sensitive
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    inhibited by ouabain
    PKC activation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS