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FLASH GENE
Symbol ATP11B contributors: mct/npt - updated : 02-02-2013
HGNC name ATPase, class VI, type 11B
HGNC id 13553
Location 3q27.1      Physical location : 182.511.290 - 182.639.419
Synonym name
  • related to mus chromaffin granule ATPase II homolog
  • probable phospholipid-transporting ATPase IF
  • Synonym symbol(s) KIAA0956, ATPIF, ATPIR, DKFZP434J238, DKFZP434N1615, MGC46576
    EC.number 3.6.3.1
    DNA
    TYPE like-sequence
    STRUCTURE 128.13 kb     30 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC391596 3 similar to 60S ribosomal protein L7a (Surfeit locus protein 3) (PLA-X polypeptide) SOX2 3q26.3-q27 SRY (sex determining region Y)-box 2 LOC391597 3 similar to ribosomal protein L7-like 1 ATP11B 3q27 ATPase, Class VI, type 11B RP42 3q26.3 RP42 homolog MCCC1 3q25-q27 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) LAMP3 3q27 lysosomal-associated membrane protein 3 RNU3P4 3q27.3 RNA, U3 small nucleolar pseudogene 4 KIAA0861 3q27.3 Rho family guanine-nucleotide exchange factor B3GNT5 3q28 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 KLHL6 3q27.3 kelch-like 6 (Drosophila) DRE1 3q27.3 DRE1 protein FLJ10201 3q27.3 hypothetical protein FLJ10201 FLJ12748 3q27.3 hypothetical protein FLJ12748 PSARL 3q27.3 presenilin associated, rhomboid-like LOC391598 3 similar to 40S ribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag) LOC391599 3 similar to cytochrome P450 2P1 ABCC5 3q27 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 LOC389179 3 similar to Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu) HTR3D 3q27.3 5-hydroxytryptamine receptor 3 subunit D HTR3C 3q27.3 5-hydroxytryptamine receptor 3 subunit C LOC389180 3 similar to 5-hydroxytryptamine receptor 3 subunit C HTR3E 3q27.3 5-hydroxytryptamine serotonin receptor 3E
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    30 - 7347 134 1177 - 2001 11058586
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     thymus   highly
    Nervousbrain    
    Reproductivemale systemtestis   
    Urinarybladder   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a KVIRLIKIS sequence in the catalytic loop of ATP11B
  • HOMOLOGY
    interspecies homolog to mus chromaffin granule ATPase II
    Homologene
    FAMILY
  • cation transport ATPase (P-type) family
  • type IV subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,endosome
    intracellular,nuclear envelope,int
    text integral membrane protein
    basic FUNCTION RING finger-binding protein that targets transcription factors to specific domains within the nucleus
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TMEM30 is not essential for the ER exit or TGN localization of ATP9B, whereas TMEMA, but not TMEM30B, is required for ER exit and/or recycling endosomal localization of ATP11B
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS