| basic FUNCTION
| copper chaperone playing a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin |
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involved in copper homeostasis (perinatal copper homeostasis) |
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copper-dependent transcription factor that mediates copper-induced cell proliferation |
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functions as a novel transcription factor that, when activated by copper, undergoes nuclear translocation, DNA binding, and transactivation, thereby contributing to cell proliferation |
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might have acquired nuclear function in addition to its copper chaperone function for the secretory compartment during the course of evolution |
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may contribute to hyperproliferative conditions such as cancer, angiogenesis, and atherosclerosis |
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copper chaperone with the ferredoxin-like fold that binds Cu(I) via two Cys residues in a M(10)X(11)C(12)X(13)X(14)C(15) motif located in a solvent-exposed loop  |
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important role, not only as a metallochaperone for delivering Cu to cuproenzymes, but also as a key player in maintaining the proper distribution and organization of Cu at the cellular level |
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transcription factor that upregulates prion protein expression, and intron 1 plays a key role in regulation of prion protein expression levels |
