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FLASH GENE
Symbol ATG9B contributors: mct/ - updated : 13-12-2005
HGNC name ATG9 autophagy related 9 homolog B (S. cerevisiae)
HGNC id 21899
Location 7q36.1      Physical location : 150.709.305 - 150.721.586
Synonym name
  • nitric oxide synthase 3 antisense
  • autophagy 9-like 2
  • endothelial nitric oxide synthase antisense
  • protein sONE
    • Synonym symbol(s) SONE, APG9L2, NOS3AS
    DNA
    TYPE functioning gene
    SPECIAL FEATURE overlapping, antisens
    text overlapping in antisense the NOS3 gene
    STRUCTURE 12.29 kb     17 Exon(s)
    text structure is a vertebrate-specific gene
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    17 - 4577 - 924 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineneuroendocrine   highly
     pancreas   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • ATG9 family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • participating in the post-transcriptional regulation of the endothelial nitric-oxide synthase (NOS3) gene through its antisense overlap
  • with ATG12, ATG5, ATG2B, are autophagy-related genes, having mononucleotide repeats with seven or more nucleotides
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral somatic mutation      
    in gastric and colorectal cancers with microsatellite instability
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS