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FLASH GENE
Symbol ASB6 contributors: npt/ - updated : 19-09-2006
HGNC name ankyrin repeat and SOCS box-containing 6
HGNC id 17181
Location 9q34.13      Physical location : 132.396.882 - 132.404.444
Synonym symbol(s) ASB-6, FLJ20548, MGC1024
DNA
TYPE functioning gene
STRUCTURE 7.56 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 4653 47.1 421 - Kile
- - 4544 22.2 197 - Kile
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six N terminal ankyrin (ANK) repeats
  • a conserved C-terminal SOCS box motif
  • HOMOLOGY
    interspecies ortholog to murine Asb6
    Homologene
    FAMILY
  • ankyrin repeat and SOCS box containing (ASB) family of proteins
  • CATEGORY regulatory , signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    CELLULAR PROCESS protein, post translation, targeting
    protein, degradation
    protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    intracellular signaling cascade
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • JAK kinases
  • activated cytokine receptors
  • elonguin B/C complex
  • cell & other
    REGULATION
    induced by cytokines
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS