basic FUNCTION
| regulating actin filament reorganization and neurons differentiation (regulation of calcium dependent exocytosis) |
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GTP activating protein for CDC42 and RAC1 |
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involved in regulation of Cdc42, being necessary for maintenance of tight junctions |
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maintaining tight junctions integrity by the coordinate regulation of Cdc42 and by linking specific components of the TJ to intracellular protein trafficking, when binding to AMOT |
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Acting as an aminoacyl-tRNA ligase |
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catalyzing GTP hydrolysis on CDC42 and RAC1, but not on RHOA |
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RHOGAP regulating cytoplasmic protein explored in the central nervous system |
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controls RHOA-mediated stress fibre and focal adhesion formation |
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role of NADRIN, in the morphological differentiation of astrocytes |