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FLASH GENE

Symbol

ARHGAP15

contributors: npt/ - updated : 29-08-2003

HGNC name	Rho GTPase activating protein 15
HGNC id	21030

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	2q22.3      Physical location : 143.886.898 - 144.525.920
Synonym name	uncharacterized bone marrow protein BM046
Synonym symbol(s)	BM046

DNA

TYPE	functioning gene
STRUCTURE	638.96 kb     14 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ARHGAP15 14 - 1774 54.4 475 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a pleckstrin homology (PH) domain
	a RhoGAP domain
	a novel motif N-terminal to the GAP domain
	this novel motif was found to be responsible for nucleotide-independent Rac1 binding

HOMOLOGY

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION

potential regulator of Rac1

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS