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FLASH GENE
Symbol ARHGAP15 contributors: npt/ - updated : 29-08-2003
HGNC name Rho GTPase activating protein 15
HGNC id 21030
Location 2q22.3      Physical location : 143.886.898 - 144.525.920
Synonym name uncharacterized bone marrow protein BM046
Synonym symbol(s) BM046
DNA
TYPE functioning gene
STRUCTURE 638.96 kb     14 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 1774 54.4 475 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a pleckstrin homology (PH) domain
  • a RhoGAP domain
  • a novel motif N-terminal to the GAP domain
  • this novel motif was found to be responsible for nucleotide-independent Rac1 binding
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • potential regulator of Rac1
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS