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FLASH GENE
Symbol ARF3 contributors: - updated : 22-04-2006
HGNC name ADP-ribosylation factor 3
HGNC id 654
Location 12q13.1      Physical location : 49.329.991 - 49.351.252
Synonym name small GTP binding protein
DNA
TYPE functioning gene
STRUCTURE 21.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - polyA site 3700 - - - Tsai
- - polyA site 1200 - - - Tsai
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   highly
Endocrineneuroendocrinepituitary  highly
Nervousbrain   predominantly
Reproductivefemale systembreastmammary gland highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • small GTPase superfamily
  • ADP-ribosylation factors (ARF) family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • a guanine nucleotide dependent protein activator of cholera toxin, involved in vesicular trafficking and activation of phospholipase D
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • low molecular weight GTP binding
  • interacting with PICK1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS