basic FUNCTION
| involved in transcellular endothelial fluid transport |
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playing a role in cell migration and vessel formation |
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may have a role during osmotic stresses including ischemia/reperfusion and cardiopulmonary by pass |
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‘‘orthodox’’aquaporin, that transport only water molecules (Sorani 2008) |
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represents an important distinguishing characteristic of olfactory ensheathing glia, which may impart unique function to these glia |
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play pivotal roles in cerebral water movement as essential mediators during edema and fluid accumulation |
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in inner ear plays an important role in the development of motion sickness (MS) |
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critical participate in regulating endothelial permeability and barrier function, providing direct evidence of the contribution of AQP1 to blood vessel formation |
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involvement of AQP1 in oral sensory transduction |
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constitutively open channel that closes mediated by membrane-tension increments |
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plays a crucial role in estrogen-induced tubulogenesis of vascular endothelial cells |
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cooperative role of AQP1 and SLC4A11 in mediating trans-endothelial water reabsorption |
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controls potentially both proliferation and migration in pulmonary arterial smooth muscle cell (PASMC) and the mechanism requires the C-terminal tail of the protein but is independent of water transport or the EF-hand motif |
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endothelial expression of AQP1 characterizes the atheroprotected, non-inflamed vessel wall |