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FLASH GENE
Symbol APOL4 contributors: mct - updated : 29-01-2004
HGNC name apolipoprotein L, 4
HGNC id 14867
Location 22q13.1      Physical location : 36.585.177 - 36.600.879
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text APOL1-APOL4 are clustered on human chromosome 22q13.1
STRUCTURE 15.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3417 - 340 - Monajemi
- - 3228 - 351 - Monajemi
- - 969 - 107 - Monajemi
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly
Endocrineadrenal gland   highly
 pancreas   lowly
Nervousbrain   lowly
 spinal cord   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conserved amphipathic alpha helices
HOMOLOGY
Homologene
FAMILY APOL family
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION may be participating in reverse cholesterol transport from peripheral cells to the liver
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS