Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol APOC4 contributors: - updated : 31-05-2006
HGNC name apolipoprotein C-IV
HGNC id 611
Location 19q13.2      Physical location : 45.445.494 - 45.448.751
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text APO-C cluster
STRUCTURE 3.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
LOC147711 19q13.32 similar to zinc finger protein 285 ZNF180 19q13.1-q13.3 zinc finger protein 180 (HHZ168) UNQ9366 19q13.32 GPAD9366 LOC388550 19 similar to CEACAM5 protein LOC390941 19 LOC390941 LOC147710 19q13.32 hypothetical LOC147710 PVR 19q13.2 poliovirus receptor CEAL1 19q13.32 carcinoembryonic antigen-like 1 LOC388551 19 similar to carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) BCL3 19q13.2 B-cell CLL/lymphoma 3 CBLC 19q13.2-q13.3 Cas-Br-M (murine) ecotropic retroviral transforming sequence c LU 19q12-q13 Lutheran blood group (Auberger b antigen included) PVRL2 19q13.2-q13.4 poliovirus receptor-related 2 (herpesvirus entry mediator B) TOMM40 19q13 translocase of outer mitochondrial membrane 40 homolog (yeast) APOE 19q13.2 apolipoprotein E APOC1 19q13.2 apolipoprotein C-I APOC4 19q13.2 apolipoprotein C-IV APOC2 19q13.2 apolipoprotein C-II CLPTM1 19q13.2 cleft lip and palate associated transmembrane protein 1 RELB 19q13.32 v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian) SFRS16 19q13.3 splicing factor, arginine/serine-rich 16 (suppressor-of-white-apricot homolog, Drosophila) ZNF342 19q13.32 zinc finger protein 342 GEMIN7 19q13.32 gem (nuclear organelle) associated protein 7 EIF5AP3 19q13.2 eukaryotic translation initiation factor 5A pseudogene 3 LOC284352 19q13.32 hypothetical protein LOC284352 FLJ33600 19q13.32 FLJ33600 protein MGC2650 19q13.32 hypothetical protein MGC2650 LOC388552 19 similar to BC043666 protein XTP7 19q13.32 protein 7 transactivated by hepatitis B virus X antigen (HBxAg) MARK4 19q13.2 MAP/microtubule affinity-regulating kinase 4 CKM 19q13.2 creatine kinase, muscle LOC390943 19 similar to 40S ribosomal protein S16 KLC2L 19q13.3 similar to 40S ribosomal protein S16 ERCC2 19q13.3 excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
regionally located located 0.5 kb 5' to the APOC2 gene
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   predominantly
Respiratorylung   lowly
cells
SystemCellPubmedSpeciesStageRna symbol
Digestivehepatocyte
cell lineage
cell lines
fluid/secretion plasma
at STAGE
PROTEIN
PHYSICAL PROPERTIES Amphiphilic
STRUCTURE
motifs/domains
  • a 25 AA signal peptide
  • two potential amphipathic alpha helix domains
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Apoc4
    Homologene
    FAMILY apolipoprotein family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION participating in lipoprotein metabolism
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text lipid transport
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS