Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | APBB2 | contributors: mct - updated : 31-10-2012 |
HGNC name | amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) |
HGNC id | 582 |
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Location | 4p14 Physical location : 40.812.044 - 41.216.635 |
Synonym name | |
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Synonym symbol(s) | FE65L, FE65L1, Zfra |
DNA |
TYPE | functioning gene |
STRUCTURE | 404.59 kb 17 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to murine Fe65 like gene |
homolog to murine Apbb2 |
Homologene |
FAMILY | Fe65 family |
CATEGORY | adaptor |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,nucleus |
basic FUNCTION | |
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CELLULAR PROCESS | cell life, cell death/apoptosis |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to late onset Alzheimer disease |
Variant & Polymorphism SNP | associated to to late onset Alzheimer disease |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |