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FLASH GENE
Symbol AMY2B contributors: npt/ - updated : 02-02-2004
HGNC name amylase, alpha 2B (pancreatic)
HGNC id 478
Location 1p21      Physical location : 104.097.321 - 104.122.147
Synonym name
  • 1,4-alpha-D-glucan glucanohydrolase 2B
  • alpha-amylase carcinoid
  • glycogenase
    • Synonym symbol(s) AMY2
    EC.number 3.2.1.1
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text see AMY@
    STRUCTURE 24.83 kb     12 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 2215 56 511 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to Drosophila Amy-d
    homolog to C.elegans C50B6.7
    Homologene
    FAMILY
  • glycosyl hydrolase 13 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the endohydrolysis of 1,4-alpha-glucosidic linkages in oligosaccharides and polysaccharides
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS digestion
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Ca2+
  • chloride Cl2-
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS