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FLASH GENE
Symbol AMY2A contributors: - updated : 16-02-2006
HGNC name amylase, alpha 2A; pancreatic
HGNC id 477
Location 1p21      Physical location : 104.159.998 - 104.168.393
Synonym name 1,4-alpha-D-glucan glucanohydrolase
Synonym symbol(s) AMY2
EC.number 3.2.1.1
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 42.00 kb     10 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked Y status confirmed
Map see AMY@
Physical map
FLJ10287 1pter-q31.3 hypothetical protein FLJ10287 MGC14816 1p21.3 hypothetical protein MGC14816 DBT 1p31 dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) RTCD1 1p21.1 RTC domain containing 1 CDC14A 1p22 CDC14 cell division cycle 14 homolog A (S. cerevisiae) GPR88 1p21.3 G-protein coupled receptor 88 LOC391060 1 similar to 60S ribosomal protein L7a (Surfeit locus protein 3) (PLA-X polypeptide) LOC391061 1 similar to large subunit ribosomal protein L36a VCAM1 1p21 vascular cell adhesion molecule 1 EXTL2 1p12-p11 exostoses (multiple)-like 2 SLC30A7 1p21.2 solute carrier family 30 (zinc transporter), member 7 CGI-30 1p21.2 CGI-30 protein FLJ20139 1p21.2 hypothetical protein FLJ20139 EDG1 1p21 endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 LOC391062 1 similar to peptidylprolyl isomerase A (cyclophilin A) LOC388654 1 similar to 40S ribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag) OLFM3 1p22-p21 olfactomedin 3 HEJ1 1p22 olfactomedin 3 COL11A1 1p21 collagen, type XI, alpha 1 LOC388655 1 LOC388655 FLJ25070 1p21 hypothetical protein FLJ25070 AMY2B 1p21 amylase, alpha 2B; pancreatic AMY2A 1p21 amylase, alpha 2A; pancreatic AMY1A 1p21 amylase, alpha 1A; salivary LOC388656 1 hypothetical gene supported by BC014218 LOC391063 1 similar to Ferritin light chain (Ferritin L subunit) LOC391064 1 hypothetical gene supported by AK001388 LOC126987 1p13.3 similar to tight junction protein 3 (zona occludens 3)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas   highly
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Amy2
homolog to Drosophila Amy-p
homolog to C.elegans C50B6.7
Homologene
FAMILY family 13 of glycosyl hydrolases or alpha-amylase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION having a hydrolase activity acting on glycosyl bonds
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism carbohydrate
signaling
a component
INTERACTION
DNA
RNA
small molecule metal binding, cofactor,
  • calcium Ca2+
  • chloride Cl-
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS