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FLASH GENE

Symbol

AMY2A

contributors: - updated : 16-02-2006

HGNC name	amylase, alpha 2A; pancreatic
HGNC id	477

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	1p21      Physical location : 104.159.998 - 104.168.393
Synonym name	1,4-alpha-D-glucan glucanohydrolase
Synonym symbol(s)	AMY2
EC.number	3.2.1.1

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
STRUCTURE	42.00 kb     10 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

Y

status

confirmed

Map

see AMY@

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine pancreas       highly Nervous brain       moderately Reproductive male system prostate     moderately Respiratory lung       moderately

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	ortholog to murine Amy2
	homolog to Drosophila Amy-p
	homolog to C.elegans C50B6.7

Homologene

FAMILY

family 13 of glycosyl hydrolases or alpha-amylase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION

having a hydrolase activity acting on glycosyl bonds

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

carbohydrate

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding, cofactor,
	calcium Ca2+
	chloride Cl-

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS