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FLASH GENE

Symbol

AMIGO3

contributors: - updated : 18-04-2005

HGNC name	amphoterin-induced gene and ORF 3
HGNC id	24075

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3p21      Physical location : 49.754.267 - 49.757.238

DNA

TYPE	functioning gene
STRUCTURE	2.00 kb     1 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive intestine large intestine colon     Reproductive female system ovary

cells

System Cell Pubmed Species Stage Rna symbol Nervous neuron

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a signal sequence for secretion
	a transmembrane domain
	six leucine-rich repeats (LRRs)
	cysteine-rich LRR NH2- and COOH-terminal domains
	one immunoglobulin domain close to the transmembrane region

HOMOLOGY

Homologene

FAMILY

AMIGO family

CATEGORY

adhesion , regulatory

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

cell adhesion molecule specifically expressed on fiber tracts of neuronal tissues and participating in their formation

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS