Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ALPI contributors: np/ - updated : 02-02-2004
HGNC name alkaline phosphatase, intestinal
HGNC id 437
Location 2q37.1      Physical location : 233.320.832 - 233.324.740
Synonym name
  • alkaline phosphomonoesterase
  • Kasahara isozyme
    • Synonym symbol(s) IAP
    EC.number 3.1.3.1
    DNA
    TYPE functioning gene
    STRUCTURE 3.91 kb     11 Exon(s)    RaaLrInLh Copie(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type untranslated
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 2559 54.7 528 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestine    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • zinc-metalloprotein, made of a complex of identical subunits, each subunit containing one active site
  • two zinc Zn2+ molecules, and magnesium Mg2+as a cofactor
    • conjugated MetalloP
    mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • alkaline phosphatase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text Attached to the membrane by a GPI-anchor
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Zn2+
  • Mg2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS