Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ALKBH8 | contributors: mct/npt - updated : 21-06-2019 |
HGNC name | alkB, alkylation repair homolog 8 (E. coli) |
HGNC id | 25189 |
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Corresponding disease |
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Location | 11q22.3 Physical location : 107.373.453 - 107.436.461 | ||
Synonym name | |||
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Synonym symbol(s) | FLJ38204, MGC10235, ABH8 | ||
EC.number | 2.1.1.229 |
DNA |
TYPE | functioning gene |
STRUCTURE | 63.01 kb 12 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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HOMOLOGY |
interspecies | ortholog to yeast Trm9 |
Homologene |
FAMILY |
CATEGORY | RNA associated |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic,ribosome | |
intracellular,nucleus,nucleoplasm,nuclear bodies |
CELLULAR PROCESS | nucleotide, repair |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | nucleotide, |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | ALKBH8D |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
| new therapeutic strategies in human bladder cancer by inducing JNK/p38/gammaH2AX-mediated cell death by silencing of ALKBH8 (Shimada 2009) |
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ANIMAL & CELL MODELS |