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FLASH GENE
Symbol ALDH8A1 contributors: mct - updated : 03-09-2008
HGNC name aldehyde dehydrogenase 8 family, member A1
HGNC id 15471
Location 6q23.1      Physical location : 135.238.528 - 135.271.260
Synonym name
  • aldehyde dehydrogenase 12
  • cDNA FLJ77084, highly similar to Homo sapiens aldehyde dehydrogenase
  • 8 family, member A1
  • aldehyde dehydrogenase family protein
  • Synonym symbol(s) ALDH12, DJ352A20.2, DKFZp779D2315, MGC138650, hCG_32738
    EC.number 1.2.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 32.00 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    VNN1 6q23-q24 vanin 1 VNN3 6q23-q24 vanin 3 VNN2 6q23-q24 vanin 2 C6orf192 6q22.3-q23.3 chromosome 6 open reading frame 192 RPS12 6q23.1 ribosomal protein S12 LOC134870 6q23.1 similar to 60S ribosomal protein L23a EYA4 6q23 eyes absent homolog 4 (Drosophila) MGC34034 6q23.2 hypothetical protein MGC34034 TCF21 6q23-q24 transcription factor 21 FLJ35700 6q23.2 hypothetical protein FLJ35700 TBPL1 6q22.1-q22.3 TBP-like 1 SLC2A12 6q23.2 solute carrier family 2 (facilitated glucose transporter), member 12 SGK 6q23 serum/glucocorticoid regulated kinase LOC391971 6 similar to keratin 8; cytokeratin 8; keratin, type II cytoskeletal 8 LOC391972 6 similar to chromosome 7 open reading frame 17 protein; 16.7kD protein FAM8A6P 6q23 family with sequence similarity 8, member A6 pseudogene LOC154094 6q23.2 similar to Protein CGI-27 (C21orf19-like protein) ALDH8A1 6q24.1-q25.1 aldehyde dehydrogenase 8 family, member A1 HBS1L 6q23-q24 HBS1-like (S. cerevisiae) MYB 6q23.3-q24 v-myb myeloblastosis viral oncogene homolog (avian) AHI1 6q23.2 Abelson helper integration site LOC391973 6 similar to Glyceraldehyde 3-phosphate dehydrogenase, liver (GAPDH) PDE7B 6q23-q24 phosphodiesterase 7B DUFD1 6q23.2 DUF729 domain containing 1 BTF 6q23 DUF729 domain containing 1 MAP7 6q23.3 microtubule-associated protein 7 MAP3K5 6q22.33 mitogen-activated protein kinase kinase kinase 5 PEX7 6q21-q22.2 peroxisomal biogenesis factor 7 SLC35D3 6q23.2 solute carrier family 35, member D3 IL20RA 6q23.3 interleukin 20 receptor, alpha IL22RA2 6q24-q25.1 interleukin 22 receptor, alpha 2
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2549 - 487 - Lin (2000)
    6 - 2387 47 433 - Lin (2000)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    Text esophage, liver, kidney
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • aldehyde dehydrogenase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • converting 9 cis-retinal into the RXR ligand 9 cis-retinoic acid
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism vitamin
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS