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FLASH GENE

Symbol

AKTIP

contributors: npt - updated : 14-12-2004

HGNC name	AKT interacting protein
HGNC id	16710

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	16q12.2      Physical location : 53.525.192 - 53.537.170
Synonym name	fused toes homolog (mouse)
Synonym symbol(s)	FLJ13258, FT1, FTS

DNA

TYPE	functioning gene
STRUCTURE	11.00 kb     10 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

text	Variants 1 and 2 encode the same protein

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 2222 33 292 - - variant 2 - - 2193 33 292 - -

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

ubiquitin-conjugating enzyme family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

basic FUNCTION

regulator of PKB/Akt activity in the control of proliferation, differentiation, apoptosis in many cell types

CELLULAR PROCESS	cell life, differentiation
	cell life, proliferation/growth
	cell life, cell death/apoptosis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

PKB/Akt1

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS