| basic FUNCTION
| aldo-ketoreductase reducing aromatic and aliphatic aldehydes, less active on hexoses |
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playing a critical role in the growth and proliferation of cancer cells by detoxifying reactive carbonyls and regulating fatty acid biosynthesis  |
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may be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs |
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may regulate cell proliferation and cellular response to additional carbonyl stress |
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regulates the stability of acetyl-coA carboxylase-alpha and is a novel regulator of the biosynthesis of fatty acid in breast cancer cells |
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may play a greater role in lung carcinogenesis through dysregulation of reinoic acid homeostasis than through oxidation of PAH trans-dihydrodiols |
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dysregulated in Barrett's esophagus and esophageal adenocarcinoma |
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might be useful as a new marker for identification of high lung cancer risk patients in usual interstitial pneumonia |
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may play an important role in tumor progression or drug resistance |
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new secretory protein belonging to a lysosome-mediated non-classical protein-secretion pathway and is a potential serum marker |
