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FLASH GENE
Symbol AKNA contributors: - updated : 17-01-2007
HGNC name AT-hook transcription factor AKNA
HGNC id 24108
Location 9q32      Physical location : 117.096.432 - 117.156.685
Synonym name AKNA transcript F2
Synonym symbol(s) KIAA1968, RP11-82I1.4
DNA
TYPE functioning gene
STRUCTURE 58.00 kb     22 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 5026 - 1320 predominantly in the tonsil Sims-Mourtada
- splicing 4984 - 1364 in tonsil and thymus Sims-Mourtada
- splicing polyA site 2364 - 674 only in the tonsils Sims-Mourtada
a truncated exon 2, and exon3
- splicing polyA site 2177 - 612 only in the tonsils Sims-Mourtada
a truncated exon 3
- splicing 5344 - 1439 only in the thymus Sims-Mourtada
- splicing 5038 - 1358 only in the thymus Sims-Mourtada
- splicing 3189 70 640 predominantly in the tonsil Sims-Mourtada
- splicing 2315 - 405 predominantly in the tonsil Sims-Mourtada
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
 thymus    
Nervousnervecranial nerve  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoietic   highly
Connectiveadipose  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three coiled coil-4 domains
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • AT-hook transcription factor that regulates the expression of costimulatory cell surface molecules on lymphocytes
  • having functional diversity and capacity to generate multiple transcripts
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS