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FLASH GENE
Symbol AKAP2 contributors: - updated : 21-07-2003
HGNC name a kinase (PRKA) anchor protein 2
HGNC id 372
Location 9q31-q33      Physical location : 112.810.975 - 112.934.789
Synonym symbol(s) AKAPL,KIAA0920
DNA
TYPE functioning gene
STRUCTURE 163.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Map cen - D9S176 - ALDOB ALDOB - D9S271 - D9S172 - AKAP2 - D9S160 - PTPN3 - TXN - D9S174 - TNC - D9S279 - qter
Authors Gene Map (98)
Physical map
KLF4 9q31 Kruppel-like factor 4 (gut) LOC392380 9 similar to peptidylprolyl isomerase A (cyclophilin A) LOC392381 9 similar to large subunit ribosomal protein L36a LOC392382 9 similar to ribosomal protein L31 LOC347292 9q32 similar to ribosomal protein L36; 60S ribosomal protein L36 IKBKAP 9q31 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein ACTL7B 9q31 actin-like 7B ACTL7A 9q31 actin-like 7A FLJ20457 9q32 hypothetical protein FLJ20457 CTNNAL1 9q31.2 catenin (cadherin-associated protein), alpha-like 1 C9orf5 9q31 chromosome 9 open reading frame 5 EPB41L4B 9q22.1-q22.3 erythrocyte membrane protein band 4.1 like 4B FLJ21596 9q32 hypothetical protein FLJ21596 PTPN3 9q31.2 protein tyrosine phosphatase, non-receptor type 3 LOC347295 9q32 similar to DNA-binding protein B LOC389783 9 LOC389783 AKAP2 9q31-q33 a kinase (PRKA) anchor protein 2 PALM2 9q31-q33 paralemmin 2 TXN 9q31 thioredoxin LOC255220 9q32 similar to RIKEN cDNA 4930429J24 MUSK 9q31.3-q32 muscle, skeletal, receptor tyrosine kinase EDG2 9q31.3-q32 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 OR2K2 9q32 olfactory receptor, family 2, subfamily K, member 2 OR2AR1P 3p24.1 olfactory receptor, family 2, subfamily AR, member 1 pseudogene KIAA0368 9q22.3-q32 olfactory receptor, family 2, subfamily AR, member 1 pseudogene ZNF483 9 zinc finger protein 483 LTB4DH 9q32 leukotriene B4 12-hydroxydehydrogenase LOC392383 9 similar to hypothetical protein FLJ10120 GNG10 9q31-q32 guanine nucleotide binding protein (G protein), gamma 10 FLJ32779 UGCG 9q31 UDP-glucose ceramide glucosyltransferase DKFZP761E1824
RNA
TRANSCRIPTS type messenger
text several isoforms
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
respiratorylungalveoli   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cells
SystemCellPubmedSpeciesStageRna symbol
 epithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
secondary structure an amphipathic helix binding domain
HOMOLOGY
Homologene
FAMILY
CATEGORY chaperone/stress
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • a kinase,scaffold protein (PRKA regulatory subunit RIIA) anchor protein,tethering the enzyme to its physiological substrate
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS