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FLASH GENE
Symbol AIG1 contributors: mct - updated : 05-01-2013
HGNC name androgen-induced 1
HGNC id 21607
Location 6q24.1      Physical location : 143.382.022 - 143.661.439
Synonym name androgen induced protein (AIG-1), C-terminus truncated
Synonym symbol(s) AIG-1, FLJ10485, dJ95L4.1
DNA
TYPE functioning gene
STRUCTURE 279.42 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC340149 6q24.1 hypothetical LOC340149 LOC391976 6 similar to SUMO-1 activating enzyme subunit 2 NMBR 6q23 neuromedin B receptor C6orf55 6q24.1 chromosome 6 open reading frame 55 GPR126 6q23.1-q24.3 G protein-coupled receptor 126 HIVEP2 6q23-q24 human immunodeficiency virus type I enhancer binding protein 2 AIG1 6q24.1 androgen-induced 1 DEADC1 6q24.1 deaminase domain containing 1 LOC391977 6 similar to dJ20N2.2 (novel protein similar to tubulin, beta polypeptide 4, member Q (TUBB4Q)) PEX3 6q23-q24 peroxisomal biogenesis factor 3 FUCA2 6q25-qter fucosidase, alpha-L- 2, plasma C6orf56 6q24.1 chromosome 6 open reading frame 56 C6orf93 6q24.1 chromosome 6 open reading frame 93 LOC153918 6q24.1 similar to CGI-62 protein PLAGL1 6q25 pleiomorphic adenoma gene-like 1 SF3B5 6q24.1 splicing factor 3b, subunit 5, 10kDa MRPL42P3 6q24.2 splicing factor 3b, subunit 5, 10kDa STX11 6q23.1-q25.3 syntaxin 11 LOC285741 6q24.1 similar to Translationally controlled tumor protein (TCTP) (p23) (Histamine-releasing factor) (HRF) UTRN 6q24 utrophin (homologous to dystrophin) LOC391978 6 similar to ZNF131 protein EPM2A 6q24.3 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) FBXO30 6q24 F-box protein 30 SHPRH 6q24.2 SNF2 histone linker PHD RING helicase GRM1 6q24 glutamate receptor, metabotropic 1
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 1385 - 238 - 2011 21622095
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarybladder   highly
 kidney   highly
Visualeyeanterior segmentiris  
 eyeretina   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Respiratoryepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
five hydrophobic domains
HOMOLOGY
Homologene
FAMILY AIG1 family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum
basic FUNCTION may have functions in the androgen-regulated hair cycle
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • is a novel RCHY1-interacting protein, that activates the NFAT signaling pathway
    • cell & other
    REGULATION
    induced by androgens
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
  • could serve as a new biomarker for the diagnosis and prognostic evaluation of hepatocellular carcinomas (PMID;
    • Therapy target
    ANIMAL & CELL MODELS